ENTRY O1706 20081126 O038O170600000001 SUBENT O1706001 20081126 O038O170600100001 BIB 14 51 O170600100002 TITLE Production of the Auger emitter Sb-119 for targeted O170600100003 radionuclide therapy using a small PET-cyclotron. O170600100004 AUTHOR (H.Thisgaard, M.Jensen) O170600100005 REFERENCE (J,ARI,67,34,2009) O170600100006 INSTITUTE (2DENRIS) O170600100007 (2DENCOP) O170600100008 SAMPLE Sn-119 metal, enriched to 97.4%, was rolled to two thinO170600100009 foils with mean thicknesses of 5.34 and 11.73 mg/cm**2,O170600100010 respectivily. The thicknesses were determined from the O170600100011 weight and area of the foils. O170600100012 FACILITY (CYCLO,2DENRIS) The PET cyclotron O170600100013 DETECTOR (GE) A calibrated Ge detector was used for measuring O170600100014 the monitor foils and the enriched Sn-119 foils for anyO170600100015 produced Sb-118-m and other impurities. O170600100016 (SILI) For determining the produced Sb-119 activities O170600100017 a calibrated Si(Li) detector or a low-energy Ge O170600100018 detector was used. O170600100019 CORRECTION The Sb-119 activities were corrected for any O170600100020 simultaneously produced Sn-119-m(T(1/2)=293.1 d), whichO170600100021 emits a single gamma-ray of the same energy-23.87 keV, O170600100022 by measuring the targets after the Sb-119 had decayed. O170600100023 The attenuation of the 23.87 keV gamma-ray in the O170600100024 Sn-119 foils was calculated to be maximum 8%. O170600100025 METHOD (STTA) O170600100026 (ACTIV) O170600100027 (EXTB) three stacks were irradiated for 20 min using O170600100028 the external proton beam. O170600100029 (BCINT) O170600100030 (CHSEP) O170600100031 MONITOR (29-CU-0(P,X)30-ZN-63,,SIG) O170600100032 (29-CU-0(P,X)30-ZN-62,,SIG) precision Cu monitor foils O170600100033 were used in all stacks to determine the energy of theO170600100034 beam via the monitor reactions. O170600100035 ADD-RES The measured beam current from the Faraday-cup-like O170600100036 target holder is reported also. O170600100037 A calculation of the thick target Sb-119 yield in O170600100038 saturation per muA based on the fit to the measured O170600100039 cross sections was made and reported on figure 4. O170600100040 ERR-ANALYS (ERR-T).The total uncertainty of each cross section is O170600100041 6-7% and was calculated by combining the contributing O170600100042 errors in quadrature- O170600100043 (ERR-1).Error in beam current. O170600100044 (ERR-2).Error in target foil thickness. O170600100045 (ERR-3,4.0,6.0).Error in activity measurement is 4-6%, O170600100046 including detector efficiency 3%. O170600100047 (ERR-4).Error in detector efficiency . O170600100048 (ERR-5,3.0,5.0).Error in nuclear data is 3-5%. O170600100049 (ERR-6).Errors due to counting statistics. O170600100050 (EN-ERR).The energy error is reported in table. O170600100051 STATUS (TABLE) Table 1 O170600100052 HISTORY (20081126C) SB O170600100053 ENDBIB 51 0 O170600100054 COMMON 4 3 O170600100055 ERR-1 ERR-2 ERR-4 ERR-6 O170600100056 PER-CENT PER-CENT PER-CENT PER-CENT O170600100057 5. 3. 3. 1. O170600100058 ENDCOMMON 3 0 O170600100059 ENDSUBENT 58 0 O170600199999 SUBENT O1706002 20081126 O038O170600200001 BIB 3 3 O170600200002 REACTION (50-SN-119(P,N)51-SB-119,,SIG) O170600200003 RAD-DET (51-SB-119,DG) O170600200004 DECAY-DATA (51-SB-119,38.19HR,DG,23.87) O170600200005 ENDBIB 3 0 O170600200006 NOCOMMON 0 0 O170600200007 DATA 4 6 O170600200008 EN EN-ERR DATA ERR-T O170600200009 MEV MEV B B O170600200010 9.9 0.18 0.73 0.05 O170600200011 11.0 0.15 1.08 0.07 O170600200012 12.3 0.14 1.04 0.07 O170600200013 12.9 0.14 0.79 0.05 O170600200014 14.0 0.10 0.45 0.03 O170600200015 15.2 0.10 0.267 0.017 O170600200016 ENDDATA 8 0 O170600200017 ENDSUBENT 16 0 O170600299999 SUBENT O1706003 20081126 O038O170600300001 BIB 2 2 O170600300002 REACTION (50-SN-119(P,2N)51-SB-118-M,,SIG) O170600300003 DECAY-DATA (51-SB-118-M,5.0HR) O170600300004 ENDBIB 2 0 O170600300005 NOCOMMON 0 0 O170600300006 DATA 4 4 O170600300007 EN EN-ERR DATA ERR-T O170600300008 MEV MEV B B O170600300009 12.3 0.14 0.0119 0.0008 O170600300010 12.9 0.14 0.0290 0.0018 O170600300011 14.0 0.10 0.061 0.004 O170600300012 15.2 0.10 0.107 0.007 O170600300013 ENDDATA 6 0 O170600300014 ENDSUBENT 13 0 O170600399999 ENDENTRY 3 0 O170699999999